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. 2018 Dec 13;9:1059. doi: 10.3389/fneur.2018.01059

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Copyright © 2018 Zeng, Wang, Guo, Zheng, Wang, Wu, Li, Wu, Chen, Xu, Wang and Lin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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SNX27 haploinsufficiency suppresses the proliferation of macrophage/microglia after SCI. (A) Immunohistological analysis of horizontal spinal cord sections from Snx27^+/+ mice and Snx27^+/− mice 7 days post injury using antibodies against Iba1 and Ki67 in horizontal sections. Arrowheads indicate Ki67⁺Iba1⁺ cells. (B) Quantification of Ki67⁺Iba1⁺ cells at the area which is ranging from rostral 400 μm (−400 μm) to caudal 400 μm (+400 μm) around the LC, n = 3. Values are expressed as mean ± SEM and were evaluated by Student's independent sample t-test. **p < 0.01.