Table 2.
Main differences regarding DNA repair-related proteins in Deinococcus species.
| Protein | Drad | Dgeo | Ddes | Dmar | Dgob | Dpro | Dper | Dswu | Dsol | Dact | Dpun |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BER, MMR, direct reversal and novel two-domain proteins | |||||||||||
| Mpg | 1 | 1 | 1 | 2 | 2 | 1 | 1 | 2 | 2 | 2 | 1 |
| AlkD | 1 | ||||||||||
| Ung | 1 | 1 | 1 | 1 | 1 | 1 | 1 | ||||
| Udg4 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | |||
| Udg DR_0022 | 1 | ||||||||||
| Nfi | 1 | 1 | 1 | 1 | 1 | ||||||
| XthA | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 |
| Dam | 1 | 1 | |||||||||
| Dcm | 1 | 1 | 4 | 2 | 2 | ||||||
| DR_C0020 | 1 | ||||||||||
| Vsr | 1 | 1 | 1 | 1 | |||||||
| Ada | 1 | ||||||||||
| PhrB | 1 | 2 | 2 | 1 | |||||||
| SplB | 1 | 1 | 1 | ||||||||
| AdaA-AlkA | 1 | 1 | 1 | ||||||||
| PhrB-Ung | 1 | 1 | 1 | 1 | 1 | ||||||
| Nth-Dcm | 1 | ||||||||||
| Dut | 1 | 1 | |||||||||
| Dcd | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |||
| Deglycase | 2 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 2 | |
| Nucleotide excision repair | |||||||||||
| UvrA2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | |
| SSL2 helicase | 1 | 1 | 1 | 1 | 2 | 4 | 1 | ||||
| Recombinational repair | |||||||||||
| RecA | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 |
| RecB/AddA | 1 | ||||||||||
| RecQ | 1 | fr | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| RusA (YbcP) | 1 | 2 | |||||||||
| SSB | 1 | 4 | 1 | 1 | 3 | 4 | 1 | 1 | 1 | 1 | 1 |
| Ligases and adjacent genes | |||||||||||
| LigA | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| DR_B0100 | 1 | 1 | 1 | 1 | 1 | ||||||
| DR_B0099 | 1 | 1 | |||||||||
| DR_B0098 | 1 | 1 | 1 | 1 | 1 | ||||||
| DR_B0094 | 1 | 1 | 1 | ||||||||
| DR_B0095 | fr | 1 | |||||||||
| Other DNA repair proteins | |||||||||||
| TopA | 1 | 1 | 1 | 2 | 3 | 2 | 2 | 1 | 1 | 1 | 1 |
| Exo (Xni) | 1 | 1 | |||||||||
| NERD domain | 1 | 1 | 1 | 1 | |||||||
| NucS (EndoMS) | 1 | 2 | 1 | fr | 1 | 1 | 1 | ||||
| PolB | 1 | 1 | 1 | 1 | |||||||
| DnaE2 | 1 | 1 | |||||||||
| ImuY | 1 | 1 | |||||||||
| DinP | 1 | 1 | 1 | 1 | 1 | 1 | 1 | ||||
| HelD | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | |
| HepA | 2 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | ||
fr, frameshift. Names in bold indicate gene inactivation leading to increased sensitivity of D. radiodurans to radiation or oxidative stress in at least one study.