Fig. 1.

Effect of oxytocin (OXY, 0.03, 0.1, and 0.3 mg/kg; s.c., administered after arena habituation) or vehicle (VEH, 0.154 M saline 1 ml/kg) administered according to the protocol shown in a on four occasions at 7 day intervals so that each rat received every dose on b total locomotor activity (LMA, cumulative ambulatory counts, mean ± SEM), and c change in body temperature (from basal recorded 5 min pre injection, mean ± SEM, °C) in adult Lister-hooded rats (n = 12, within-subjects design) recorded in an activity box for 90 min post injection. c *P < 0.05, ***P < 0.001 VEH vs. 0.3 or 0.1 mg/kg OXY; ^##P < 0.01, ^###P < 0.001, 0.3 mg/kg OXY vs. 0.1 mg/kg OXY; ⁺⁺P < 0.01 0.3 mg/kg OXY from 0.03 mg/kg OXY; Tukey’s post hoc test