Table 4.
Clinical and laboratory parameters based on World Health Organization (WHO) histological type
| Parameter | A | AB | B | C | P‐value |
|---|---|---|---|---|---|
| Number | 4 | 27 | 6 | 9 | |
| Age (years) | 62 (62–69) | 64 (56–73) | 67 (55–78) | 59 (54–62) | 0·1 |
| Age onset | 54 (33–61) | 54 (44–60) | 60 (52–69) | 52 (40–56) | 0·1 |
| Females | 2 (50%) | 20 (74%) | 4 (67%) | 4 (44%) | 0·4 |
| Abs lymphs | 2·5 (1·9–3·2) | 1·6 (1·1–2·5) | 2·3 (1·0–2·6) | 0·8 (0·5–0·9) | 0·003 |
| Abs CD3 | 2·8 (2·3–4·1) | 1·1 (0·8–2·2) | 0·7 (0·4–1·7) | 0·7 (0·4–0·9) | 0·02 |
| Abs CD4 | 0·6 (0·3–1·0) | 0·6 (0·4–1·0) | 0·4 (0·2–) | 0·2 (0·1–0·3) | 0·02 |
| Abs CD8 | 1·4 (0·3–3·5) | 0·7 (0·2–1·5) | 0·2 (0·1–) | 0·3 (0·2–0·5) | 0·3 |
| Autoimmune | 1 (25%) | 6 (22%) | 1 (17%) | 4 (44%) | 0·6 |
| Myasthenia | 1 (25%) | 1 (4%) | 0 | 1 (11%) | 0·3 |
| RBC aplasia | 3 (9%) | 2 (7%) | 0 | 3 (33%) | 0·1 |
| Bronchiectasis | 1 (25%) | 16 (59%) | 0 | 2 (22%) | 0·02 |
Figures for continuous variables represent medians (interquartile ranges). Immunoglobulin (Ig)G measurements were all before patients started on immunoglobulin replacement. Statistical differences between groups determined by Kruskal–Wallis U‐test for continuous variables or χ2 test for discrete variables. Abs = absolute; RBC = red blood cells.