FIG 5.

Fh15 downregulates overexpression of CD38 provoked by LPS insult on the spleen macrophage population. Groups of mice were divided and treated as previously described. After gating, CD38 expression was measured in macrophages (CD11b⁺ F4/80⁺) from spleen. (A) Flow cytometry histogram showing a decrease in CD38 after Fh15 exposure 1 h post-LPS stimulation. (B) Comparison of CD38 expression by mean fluorescent intensity (MFI) values among treatments. (C) Alternative contour plots also showing Fh15’s effect on CD38 expression in LPS-treated mice.