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. 2018 Dec 19;3(6):e00623-18. doi: 10.1128/mSphere.00623-18

FIG 2.

FIG 2

rGO assay in SELEX buffer and 10% human serum. Posaconazole was spiked into SELEX buffer with and without 10% human serum. The change in fluorescein signal was taken to be aptamer released from the surface. Values of fractional release were calculated with respect to the minimum value (with only DMSO) and the maximum value (greatest change in fluorescence). The concentration dynamic range shifts in serum, as expected due to high posaconazole-protein binding.