Table 4.

Factors related to neurological improvement by the treatment

	Neurological improvement	Univariate analysis	Multivariate analysis
	Mean ± SD or n (%)	P-value	Hazard ratio (95% CI)	P-value
Age	59.5 ± 14.4	0.895
Sex
Female	454 (57.6%)	0.273
Male	216 (54.3%)
Treatment for ruptured aneurysm
Direct surgery	394 (56.8%)	0.443
Endovascular embolization	258 (56.8%)
Target vessel
Anterior circulation	603 (56.9%)	0.221
Posterior circulation	42 (48.3%)
Both circulation	19 (63.3%)
Distribution
Proximal vessel	414 (55.6%)	0.761
Distal vessel	187 (58.1%)
Diffuse type	63 (56.8%)
Responsible doctor
Supervisory doctor	205 (57.1%)	0.605
Specialist	361 (55.4%)
Non-specialist	104 (59.4%)
Anesthesia
General	48 (46.6%)	0.033*	0.82 (0.51–1.36)	0.443
Local	622 (57.5%)		–
Number of times
The first time	509 (58.9%)	0.005*	1.66 (1.22–2.26)	0.001*
Over and second times	160 (49.8%)		–
Timing
<3	273 (72.2%)	<0.001*	2.62 (1.85–3.73)	<0.001*
3–6	231 (66.8%)		1.87 (1.33–2.65)	<0.001*
>6	124 (51.5%)		–
Strategy
IA-vasodilators	529 (56.8%)
PTA	141 (55.5%)

CI: confidence interval, IA: intra-arterial, PTA: percutaneous transluminal angioplasty, SD: standard deviation, ^*Statistically significant.