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The effects of Sm on joint ankylosis in WT (a), signal STAT6 KO (b) and IL‐10 KO (c) mice are consistent with the effects of Sm on edematous changes. The open and closed symbols represent IIC‐immunized mice with and without Sm infection, respectively. Data are the mean ± standard deviation (s.d.) of the total number of hind paws with ankylosis for each mouse. *P < 0·05 and **P < 0·01, respectively (Mann–Whitney U‐test). The combined results of four independent experiments are shown.
