Figure 3.

N40 and B. microti infection affects splenic leukocytes of young and old mice differently. (A) Analyses of one young and one old representative mouse spleen cells from each infection group is shown at 11th and 17th day post-infection, respectively. (B) Although percentage of all splenic leukocytes increased in infected mice, growth was highest in B cells in N40 infected old mice, CD3+ T cells in young B. microti and coinfected mice, and CD8+ T cells in all young infected mice. Macrophage increased most prominently in B. microti infected and coinfected young mice while total FcR+ cells increased in all young and old infected mice. Each bar represents the mean ± s.d. (^*p < 0.05, ^**p < 0.01, ^***p < 0.001, ^****p < 0.0001).