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. 2018 Dec 13;5:110. doi: 10.3389/fmolb.2018.00110

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Copyright © 2018 Grant.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(Left) The ACT domain interface in E. coli PGDH showing the interaction of l-serine with specific residues. Reprinted from Grant (2012). (Top Right) The serine binding site in E. coli PGDH. The serine atoms are shown as spheres in the right-hand structure. Reprinted from Grant (2012), with permission from Elsevier © 2011. (Bottom Left) The serine binding site in M. tuberculosis PGDH. The serine atoms are shown as spheres in the left-hand structure. Reprinted from Grant (2012), with permission from Elsevier © 2011.