Table 2.
Model 1 |
Model 2 |
Model 3 |
Model 4 |
|||||
---|---|---|---|---|---|---|---|---|
Variable | OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value |
Age | 0.009 | 0.003 | 0.002 | 0.006 | ||||
< 50 | NA | NA | NA | NA | ||||
50–60 | NA | NA | NA | NA | ||||
61–65 | 0.25 (0.03–2.1) | 0.2 | 0.24 (0.03–2.0) | 0.2 | 0.25 (0.03–2.1) | 0.2 | 0.26 (0.03–2.2) | 0.2 |
66–70 | 1 | Ref | 1 | Ref | 1 | Ref | 1 | Ref |
71–75 | 1.1 (0.35–3.3) | 0.9 | 1.1 (0.36–3.4) | 0.9 | 1.1 (0.36–3.4) | 0.9 | 1.1 (0.35–3.3) | 0.9 |
76–80 | 1.3 (0.43–4.2) | 0.6 | 1.5 (0.47–4.5) | 0.5 | 1.4 (0.47–4.5) | 0.5 | 1.3 (0.43–4.2) | 0.6 |
81–85 | 2.7 (0.85–8.4) | 0.09 | 3.0 (0.94–8.3) | 0.06 | 3.0 (0.95–9.3) | 0.06 | 2.7 (0.85–8.5) | 0.09 |
> 85 | 6.9 (2.2–21.9) | 0.001 | 7.9 (2.5–24.7) | < 0.001 | 8.3 (2.6–26.3) | < 0.001 | 7.4 (2.3–23.5) | 0.001 |
Male sex | 1.6 (0.79–3.3) | 0.2 | 1.8 (0.86–3.6) | 0.1 | 1.8 (0.87–3.6) | 0.1 | 1.6 (0.79–3.33) | 0.2 |
Diabetes | 0.04 | 0.03 | 0.07 | 0.07 | ||||
Insulin-dependent | 4.5 (1.3–15.3) | 0.02 | 5.0 (1.5–16.7) | 0.009 | 3.7 (1.1–12.6) | 0.04 | 3.6 (1.1–12.4) | 0.04 |
Non-insulin-dependent | 0.69 (0.16–2.9) | 0.6 | 1.3 (0.58–2.8) | 0.6 | 0.59 (0.14–2.5) | 0.5 | 0.56 (0.13–2.4) | 0.4 |
Cardiovascular disease | 2.8 (1.3–5.8) | 0.006 | – | – | – | – | 2.4 (1.1–5.0) | 0.02 |
Anemiaa | 1.2 (0.5–2.5) | 0.7 | ||||||
Hypercholesterolemia | – | – | – | – | 2.7 (1.3–5.9) | 0.01 | 2.3 (1.1–5.1) | 0.03 |
Anticoagulant treatmentb | – | – | 1.4 (0.50–4.2) | 0.5 | – | – | – | – |
Number of patients included in analysis differs from the total number of patients due to missing data. NA: not available due to lack of data.
Hb <13 g/dL for both men and women.
Vitamin K antagonists or new oral anticoagulants (NOAC).