Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jun 5;27(12):1778–1788. doi: 10.1177/0963689718773361

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Fig 1. — This figure demonstrates the mechanisms of post-stroke pathophysiology. Apoptosis, neuroinflammation, oxidative stress and blood–brain barrier (BBB) disruption with brain edema are the main avenues that research tries to focus on to decrease the consequences of stroke. Different types of microRNAs and their targets are involved in the pathophysiology of stroke.

C/EBP: CCAAT/enhancer binding protein; FasL: Fas ligand; HO-1: hemeoxygenase-1; MMP: matrix metalloproteinase; NF-κB: nuclear factor kappa-light-chain-enhancer of activated B cells; ROS: reactive oxygen species; SOD: superoxide dismutase; TLR: Toll-like receptor.