Table 2.
Type of mechanisms | Type of diseases | miRNA involved | References |
---|---|---|---|
Apoptosis | ischemic stroke | miR-298, miR-21, miR-155, miR-99a, miR-106b-5p, miR-497, miR-181a, miR134, miR-384-5p | 55–63 |
hemorrhagic stroke | miR-298, miR-132, miR126, miR-103-3p | 55,64–66 | |
Neuroinflammation | ischemic stroke | miR-424, miR-let-7c-5p, miR-124, miR-181c, miR132 | 83–90 |
hemorrhagic stroke | miR132, miR-367, miR-223 | 64,91 | |
BBB disruption/brain edema | ischemic stroke | miR-130a | 115 |
hemorrhagic stroke | miR-132, miR-103-3p | 64,66 | |
Oxidative stress | ischemic stroke | miR-93, miR-424, miR-106b-5p, miR-23a-3p, miR-145 | 105–109 |
hemorrhagic stroke | miR-27b | 110 | |
Neurogenesis | ischemic stroke | miR-Let7f, miR-134, MiR-107, miR-30-5p, miR-21, miR-34a | 118,120–122 |
hemorrhagic stroke | miR-126 | 123 | |
Angiogenesis | ischemic stroke | miR-210 | 126 |
hemorrhagic stroke | miR-129-5p, miR126 | 65,127 |
BBB: blood–brain barrier; miRNA: microRNA