. 2018 May 30;27(12):1798–1808. doi: 10.1177/0963689718768455

Table 1.

Functions of Pericytes in Stroke.

Functions	Stroke types	Roles	References
Cerebral blood flow control	Ischemic stroke	Capillary constriction	^22,35,36,37
BBB maintenance	Intracerebral hemorrhage	Regulation of vessel stability and vascular permeability	^11,12,25
	Intracerebral hemorrhage	Regulation of contractile capability	^38,39
	Intracranial hemorrhage	Regulation of endothelial cell permeability	^40–42
	Ischemic stroke	Pericyte survival Modulation of BBB integrity and VEGF/Nox4/ROS expression	^43,44 ^45–49
Angiogenesis	Ischemic stroke	Revascularization	^23,46,50
		Blood vessel stabilization	^47,51,52
		Disruption of vascular integrity	^53,54
		Regulation of basement membrane formation	⁵⁵
	Hemorrhagic stroke	Vascular development	⁵⁶
	Hemorrhagic stroke	Vessel stabilization	⁵⁷
Immunological properties	Ischemic Stroke	Differentiating into microglia-like cells and performing microglia-like functions	^58,59,60,61
Immunological properties	Ischemic Stroke	Reprogramming into NPCs	^60,62
Scar formation and fibrosis	Ischemic stroke	Neuroprotection	²¹
Scar formation and fibrosis	Ischemic stroke	Promoting fibrosis and regulating fibronectin deposition	^63,64

BBB: blood–brain barrier; NPCs: neural precursor cells ; ROS: reactive oxygen species; VEGF: vascular endothelial growth factor.