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An involvement of reactive oxygen species in intracellular signaling. ROS-mediated signaling pathway is involved kinases (CaMKII, PKG, PKA, ERK, PI3K, Akt, PKC, PDK, JNK, Kinase p38), phosphatases (PTEN, PP1, other protein phosphatases), transcription factors (HIF, STAT, NF-κB), Ca2+ transport system.
