. Author manuscript; available in PMC: 2018 Dec 20.

Published in final edited form as: J Comp Neurol. 2017 Mar 23;525(9):2192–2201. doi: 10.1002/cne.24197

Table 3.

Task-based effective connectivity interactions between Parkinson’s disease subtypes OFF and ON levodopa

Hemisphere	ROI	Brodmann Area	x	y	z	peak t-score	k_E (mm³)
Left	Dorsolateral prefrontal cortex	BA 9	-29	38	29	4.69	2160
Bilateral	Thalamus (VLN)		7	-10	5	4.33	3348
Bilateral	Supplemental motor area	BA 6	7	5	65	4.32	3699
Bilateral	Middle cingulate gyrus	BA 24	-8	11	35	3.80	3375

Seed region = left posterior putamen; peak p = 0.005, cluster-corrected α < 0.05; “ON” connectivity was observed one hour after 200mg levodopa. VLN = ventrolateral nucleus