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Comparison of test characteristics at different cutoffs
| Nomogram Cutoff | Sensitivity | NPV | % of men spared a repeat biopsy | Net benefit on DCA | Number of men spared biopsy for one false negative |
|---|---|---|---|---|---|
| 19% | 97% | 91% | 27% | 0.03 | 10.5 |
| 22% | 95% | 89% | 32% | 0.04 | 8 |
| 25% | 91% | 86% | 41% | 0.06 | 6 |
| 28% | 86% | 83% | 49% | 0.08 | 5 |
| 32% | 71% | 81% | 68% | 0.13 | 4.3 |
| 35% | 57% | 77% | 76% | 0.05 | 3.3 |
DCA=Decision curve analysis
NPV=Negative predictive value
