TABLE 1.
Comparison of the Average Estimated Prostate Volumes and PSA Densities Between 100 Non-PCa and 61 PCa Patients
| Variable | Non-PCa | PCa | P-valuea |
|---|---|---|---|
| Total prostate volume (cm3) | 67.0 ± 42.3 | 46.4 ± 21.2 | 0.0001 |
| PZ volume (cm3) | 21.5 ± 6.7 | 19.5 ± 6.1 | 0.05 |
| CG volume (cm3) | 45.5 ± 39.0 | 26.9 ± 19.3 | 0.00003 |
| CG ratio | 0.62 ± 0.13 | 0.54 ± 0.12 | 0.00005 |
| PSA (ng/mL) | 8.7 ± 6.3 | 10.2 ± 13.1 | 0.13 |
| PSAD (ng/mL/cm3) | 0.15 ± 0.12 | 0.23 ± 0.24 | 0.007 |
| PSAD-CG (ng/mL/cm3) | 0.26 ± 0.24 | 0.47 ± 0.53 | 0.0005 |
PSA: prostate-specific antigen; PCa: prostate cancer; PZ: peripheral zone; CG: central gland; PSAD: PSA density; PSAD-CG: CG volume-adjusted PSA.
a
A critical value of 0.05 was used for statistical significance; after Bonferroni correction, the critical value was adjusted to 0.05/7 = 0.007.