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. Author manuscript; available in PMC: 2018 Dec 20.
Published in final edited form as: J Magn Reson Imaging. 2015 May 6;42(6):1733–1739. doi: 10.1002/jmri.24944

TABLE 3.

Classification Performance (in Terms of AUC Values) of the Total Prostate and Zonal Volumes, PSA, and PSADs for Differentiation Between Non-PCa and PCa Patients and for Differentiation Between Non-PCa and High-Gleason-Sum (Gleason Sum ≥ 7) PCa Patients

Variable Classification performance (AUC)
Non-PCa vs. PCa Non-PCa vs.
high-Gleason-sum PCa
Total prostate volume (cm3) 0.68 ± 0.04 0.70 ± 0.04
PZ volume (cm3) 0.58 ± 0.05 0.57 ± 0.05
CG volume (cm3) 0.68 ± 0.04 0.72 ± 0.04
CG ratio 0.66 ± 0.04 0.72 ± 0.04
PSA (ng/mL) 0.53 ± 0.05 0.52 ± 0.05
PSAD (ng/mL/cm3) 0.62 ± 0.05 0.65 ± 0.05
PSAD-CG (ng/mL/cm3) 0.66 ± 0.04 0.70 ± 0.04

AUC: area under the receiver operating characteristic curve; PSA: prostate-specific antigen; PCa: prostate cancer; PZ: peripheral zone; CG: central gland; PSAD: PSA density; PSAD-CG: CG volume-adjusted PSA.