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AT1aR −/− deletion reduces ENaC salt-sensitivity. Summary graphs of averaged total ENaC activity, fNPo (a); ENaC open probability, Po (b); and number of active channels fN (c) in wild type (light grey) and AT1aR −/− (dark gray) mice kept on low (<0.01% Na+), control (0.32% Na+), and high (~2% Na+) salt diet for one week, respectively. At least four different animals were tested for each condition. *significant decrease versus respective wild type values
