Figure 2.
CD8 TVM cells expand upon helminth infection. B6 (a-d, g, h) or BALB/c (e-h) IL-4 reporter mice were infected with Hp, and the draining mesLN, non-draining LN (ndLN) and spleen (Sp) were harvested at the indicated times and cells were analyzed by FACS. Plots and graphs were gated on CD4+ (a, e, h) or CD8α+ (b-d, f, g) cells. Data in (d) depict the mesLN. Data are representative of two or more independent experiments with three to five mice per group. Error bars depict the SEM. ***P < 0.001 by Student’s t test.