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. Author manuscript; available in PMC: 2019 Apr 25.
Published in final edited form as: Mucosal Immunol. 2018 Oct 25;12(1):258–264. doi: 10.1038/s41385-018-0100-x

Figure 5.

Figure 5

CD8 TVM cells are sufficient to confer innate non-cognate protection against bacterial infection. B6 WT mice were infected with Hp and naïve (CD44lo) or CD8 TVM (CD44hiCD49dlo)cells were sorted from the pooled mesLN and spleen 2 weeks later. A total of 2×106 cells were transferred into naïve IFNγ KO recipients, which were infected with 2×105 Lm the next day. Bacterial burden in liver and spleen was determined at day 3. Data were pooled from 2 independent experiments. Solid bar depicts mean. X indicates individual mice that had succumbed to infection prior to analysis. ns, not significant; *P < 0.05; **P < 0.01; ****P < 0.0001 by one-way ANOVA.