Table 2.

Adjusted linear regression comparing step count change (1000 steps) with changes in markers of inflammation, T2DM and CVD.

Characteristic	Unstandardised beta co-efficient (95% CI)	P value
Δ IL6, ng/L	−0.81 (−1.37, −0.25)	0.005
Δ CRP, mg/L	−0.68 (−1.31, −0.06)	0.033
Δ Fasting insulin, mIU/L	0.61 (−0.68, 1.90)	0.348
Δ HOMA IR	0.17 (−0.02, 0.35)	0.086
Δ Fasting glucose, mmol/L	0.17 (−0.034, 0.068)	0.509
Δ HbA1C, %	0.04 (−0.00, 0.075)	0.056
Δ LDL, mmol/L	−0.027 (−0.1, 0.045)	0.455
Δ HDL, mmol/L	−0.011 (0.07, 0.09)	0.792
Δ Diastolic BP	0.55 (−0.75, 1.84)	0.402
Δ Systolic BP	0.54 (−1.04, 2.13)	0.497
Δ Body mass index, kg/m2	−0.20 (−0.38, −0.01)	0.038

P values of <0.05 are in italics. Analyses were adjusted for age (at baseline), ethnicity, baseline step count, change in accelerometer wear-time and change in BMI. For analysis of Δ BMI vs Δ step count adjustments for age (at baseline), ethnicity, baseline step count, change in accelerometer wear-time.