. 2018 Dec 13;10:402. doi: 10.3389/fnagi.2018.00402

Table 2.

Association of SNPs of candidate genes and odds ratio to PD risk.

	Candidate Gene	SNP	Model	p-value^a	OR^a	95% CI^a
PD vs. control	GALC	Rs8005172	Allele model	0.009	0.69	(0.53, 0.92)
	GALC	Rs8005172	Additive model^c	0.010	–	–
	ZNF184	rs9468199	Allele model	0.008	1.52	(1.12, 2.08)
	ZNF184	rs9468199	Additive model^c	0.008	–	–
	IL1R2	rs34043159	Allele model	0.034	1.31	(1.02, 1.69)
	IL1R2	rs34043159	Additive model^c	0.036	–	–
	GALC	rs8005172	Dominant model	0.015	2.17	(1.18, 4.15)
	GALC	rs8005172	Dominant model^b	0.020	2.11	(1.14, 4.07)
	GALC	rs8005172	Recessive model^b	0.036	1.47	(1.03, 2.12)
	ZNF184	rs9468199	Recessive model	0.007	0.22	(0.06, 0.60)
	ZNF184	rs9468199	Recessive model^b	0.005	0.20	(0.06, 0.56)
LOPD vs. control	GALC	rs8005172	Allele model	0.016	0.71	(0.53, 0.94)
	GALC	rs8005172	Additive model^c	0.016	–	–
	GALC	rs8005172	Dominant model	0.014	2.22	(1.19, 4.29)
	GALC	rs8005172	Dominant model^b	0.011	2.39	(1.23, 4.81)
	GALC	rs8005172	Recessive model^b	0.046	1.48	(1.01, 2.18)
EOPD vs. control	ELOVL7	rs2694528	Allele model	0.032	2.24	(1.05, 4.77)
	ELOVL7	rs2694528	Additive model^c	0.029	–	–
	ZNF184	rs9468199	Allele model	0.0001	2.82	(1.62, 4.88)
	ZNF184	rs9468199	Additive model^c	0.0001	–	–
	ELOVL7	rs2694528	Dominant model	0.024	2.60	(1.10, 5.82)
	ZNF184	rs9468199	Dominant model	0.024	2.34	(1.12, 4.95)
	ZNF184	rs9468199	Recessive model	<0.0001	0.06	(0.02, 0.23)
	ZNF184	rs9468199	Recessive model^b	0.014	0.12	(0.02, 0.62)
	ELOVL7	rs2694528	Overdominant model	0.019	0.37	(0.17, 0.88)

CI: Confidence Interval, EOPD: early onset Parkinson’s disease, LOPD: late onset Parkinson’s disease, OR: odd ratio, PD: Parkinson’s Disease; SNP: single nucleotide polymorphism^.^ap-value, OR and 95% CI were obtained from risk analysis and refer to the risk allele. ^bAdjusted for age and gender. ^cp-value was calculated by Cochran-Armitage trend test for additive model.