Table 1.
Variable | Group A (n = 36) | Group B (n = 110) | Group C (n = 16) | P A vs. B | P B vs. C |
---|---|---|---|---|---|
Age in years (mean, SD) | 34 ± 13 | 48 ± 11 | 33 ± 6 | <0.001 | <0.001 |
Caucasian | 83% | 74% | 56% | 0.110 | 0.021 |
Hispanic | 0% | 14% | 38% | 0.022 | 0.028 |
Trigger/associated condition | |||||
Vasoconstrictive drugs | 53% | 67% | 25% | 0.162 | 0.002 |
Serotonergic antidepressants | 11% | 45% | 19% | <0.001 | 0.050 |
Illicit drugs | 31% | 20% | 0% | 0.189 | 0.049 |
Orgasmic/sexual | 22% | 4% | 0% | 0.002 | 0.438 |
Prior depression | 14% | 53% | 25% | <0.001 | 0.038 |
Prior migraine | 19% | 49% | 31% | 0.002 | 0.181 |
History of hypertension | 33% | 36% | 50% | 0.742 | 0.294 |
Clinical | |||||
Thunderclap headache at onset | 94% | 88% | 75% | 0.232 | 0.190 |
Admission blood pressure > 140/90 | 36% | 48% | 75% | 0.207 | 0.045 |
Systolic | 148 ± 35 | 150 ± 35 | 161 ± 35 | 0.757 | 0.262 |
Diastolic | 83 ± 16 | 82 ± 16 | 94 ± 16 | 0.672 | 0.005 |
Focal neurological sign(s) | 25% | 43% | 50% | 0.058 | 0.584 |
Seizures | 11% | 13% | 31% | 0.798 | 0.053 |
Treatment and course | |||||
Immunosuppressive therapy | 17% | 34% | 6% | 0.060 | 0.026 |
Calcium channel blocker therapy | 50% | 58% | 20% | 0.390 | 0.537 |
Clinical worsening | 3% | 18% | 13% | 0.022 | 0.576 |
Length of stay (first admission, days) | 6 ± 7 | 10 ± 9 | 10 ± 5 | 0.012 | 0.913 |
Discharge mRS score (mean) | 0.6 ± 1.4 | 0.8 ± 1.5 | 0.6 ± 1.5 | 0.614 | 0.633 |
mRS score 0–3 | 91% | 90% | 94% | 0.768 | 0.633 |
mRS score 6 (death) | 3% | 2% | 6% | 0.725 | 0.277 |
Note: Group A, men; Group B, non-pregnant women; Group C, postpartum angiopathy. Bold indicates statistically significant P values.
mRS: modified Rankin scale.