Table 6.

Gene Ontology (GO) analysis of differentially expressed mRNA in biological processes.

Term	Genes	P-Value
GO: 0017147 Wnt-protein binding	FZD8, SFRP2, WIF1, FZD2, FZD4, FZD7	<0.001
GO: 0060070 canonical Wnt signaling pathway	FZD8, CCND1, FZD2, WNT7A, FZD4, MYC, FZD7	<0.001
GO: 0007219 Notch signaling pathway	NOTCH3, HES1, NOTCH2, APH1A, DLL1, JAG1, MYC	<0.001
GO: 0042813 Wnt-activated receptor activity	FZD8, SFRP2, FZD2, FZD4, FZD7	<0.001
GO: 0007275 multicellular organism development	NOTCH2, FOXL1, SFRP2, DZIP1, DLL1, WIF1, JAG1, FZD2, FZD4	<0.001
GO: 0007220 Notch receptor processing	NOTCH3, APH1A, DLL1, JAG1	<0.001
GO: 0035567 non-canonical Wnt signaling pathway	FZD8, SFRP2, FZD2, WNT7A	<0.001
GO: 0045944 positive regulation of transcription from RNA polymerase II promoter	NOTCH3, HES1, FZD8, SFRP2, DLL1, JAG1, GLI2, WNT7A, FOSL1, MYC	<0.001
GO: 0030178 negative regulation of Wnt signaling pathway	CCND1, APC2, SFRP2, WIF1	<0.001
GO: 0000122 negative regulation of transcription from RNA polymerase II promoter	NOTCH3, HES1, FZD8, TSC22D3, CCND1, FST, GLI2, MYC	<0.001
GO: 0005515 protein binding	LOR, FZD8, APC2, APH1A, DZIP1, FST, DLL1, JAG1, FZD2, GLI2, FZD4, FZD7, NOTCH3, HES1, NOTCH2, CCND1, CD44, BCL2, KRT1, WIF1, FOSL1, IVL, MYC, ANGPT2, WNT7A	<0.001
GO: 0010812 negative regulation of cell-substrate adhesion	ANGPT2, FZD4, FZD7	<0.001
GO: 0016055 Wnt signaling pathway	APC2, SFRP2, WIF1, WNT7A, FZD4	<0.001
GO: 0030216 keratinocyte differentiation	LOR, KRT10, JAG1, IVL	<0.001
GO: 0030165 PDZ domain binding	FZD8, FZD2, FZD4, FZD7	<0.001
GO: 0001709 cell fate determination	NOTCH2, DLL1, JAG1	<0.001
GO: 0030182 neuron differentiation	FZD8, FZD2, FZD4, FZD7	<0.001
GO: 0097150 neuronal stem cell population maintenance	HES1, DLL1, JAG1	<0.001
GO: 0043066 negative regulation of apoptotic process	NOTCH2, CD44, BCL2, GLI2, WNT7A, MYC	<0.001
GO: 0033077 T cell differentiation in thymus	FZD8, BCL2, FZD7	<0.001