Table 3. Top-5 differentially active reactions (DARs) in wild type and Tn5 mutant P. putida samples.

Top-5 Differentially active reactions	Pathways	p-value
L-Alanine:3-oxopropanoate aminotransferase	Purine metabolism	0.0042
3-Aminopropanoate:2-oxoglutarate aminotransferase	Fatty acid biosynthesis	0.0043
4a-hydroxytetrahydrobiopterin dehydratase	Benzoate degradation via hydroxylation	0.0066
NADH:6,7-dihydropteridine oxidoreductase	Pyrimidine metabolism	0.0341
L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase(4-hydroxylating)	Folate biosynthesis	0.0341

Note:

The first column reports the list of the top-5 DARs (reactions with adjusted p-value < 0.05). The second column report the pathways associated to each disrupted reaction. The adjusted p-value is reported in the third column.