Table 2.

Secondary end points

	All patients N=25	VAS <4 N=6	VAS ≥4 N=19	P-value
ALP rr >30%	9 (36%)	2 (33.3%)	7 (36.8%)	0.6
Radiological response
SD	12 (48%)	2 (33.3%)	10 (52.6%)	0.3
PD	13 (52%)	4 (66.7%)	9 (47.4%)
Pre-radium-223
Analog scale for pain (VAS pain; median)	5	2	6
Post-radium-223
Analog scale for pain (VAS pain; median)	3	1.5	3

Abbreviations: PD, progressive disease; rr, response rate; SD, stable disease; VAS, visual analog scale.