Table 1. Patient characteristics.

Variable		of 224	Fraction (%)
Gender	Male / Female	196 / 28	87.5 / 12.5
Tumor localization	Oral cavity / Oropharynx	51 / 88	22.8 / 39.3
	Hypopharynx, Supraglottic larynx	70 / 15	31.2 / 6.7
cT stage	1 / 2	8 / 29	3.6 / 12.9
	3 / 4 / Missing	32 / 154 / 1	14.3 / 68.8 / 0.4
cN stage	0 / 1	18 / 11	8.0 / 4.9
	2 / 3	164 / 30	73.2 / 13.4
	Missing	1	0.5
Grade	1 / 2	6 / 145	2.7 / 64.7
	3 / 4	64 / 2	28.6 / 0.9
	Missing	7	3.1
WHO	0 / 1	17 / 181	7.6 / 80.8
	2 / 3	21 / 5	9.4 / 2.2
Smoking	Never / Yes	17 / 170	7.6 / 75.9
	Stopped / Missing	29 / 8	12.9 / 3.6
Chemotherapy	Yes	123	54.9
	No	101	45.1
p53	Negative	108	48.2
	Positive	113	50.5
	Missing	3	1.3
p16	Negative	180	80.3
	Positive	38	17.0
	Missing	6	2.7
Variable	Median (Range)
Age	58.5 (35.3–91.8)
Delivered dose (Gy)	70.6 (68.0–77.6)
Treatment time (days)	40.5 (36.0–58.0)

Abbreviations: WHO, World Health organization