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. 2018 Dec 20;13(12):e0208835. doi: 10.1371/journal.pone.0208835

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© 2018 Chohan et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — (A) Photomicrographs from Nf1^+/+ (upper panels) and Nf1^+/- (lower panels) seminiferous tubules taken at 200X showing mild to moderate degeneration of seminiferous tubules in Nf1^+/- mice (detachment of germ cells from the basal epithelium, vacuolation of the seminiferous tubule and presence of atypical residual bodies. (B) Photomicrographs from Nf1^+/+ (upper panels) and Nf1^+/- (lower panels) testes taken at 200X showing moderate alterations in spermatogenesis in Nf1^+/- mice (exfoliation of immature round spermatids and germ cells into the lumen of seminiferous tubules). (Scale bar; 50μm).