Figure 3. Influence of pH on the protein binding of moxifloxacin in human plasma (at 37°C) as determined by ultrafiltration. Mean±SD of 4 independent experiments with moxifloxacin 3 or 0.3 mg/L (total n=8) .

Abbr.: P phosphate, H HEPES, T TRIS, Pl plasma unbuffered