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. 2018 Dec 20;13(12):e0206986. doi: 10.1371/journal.pone.0206986

Fig 5. Effect of SAK3 on DA and 5-HT releases in the Cav3.1 KO hippocampus.

Fig 5

(A, C) Time zero defines the point immediately after saline or SAK3 oral administration. DA (A) and 5-HT (C) levels in the dialysate were analyzed every 6 min in the hippocampus in Cav3.1 KO mice (n = 4 per group). Error bars represent the SEM. (B, D) DA (B) and 5-HT (D) levels at time point from 0 to 60 min were calculated with the AUC (n = 4 per group). Error bars represent the SEM. **p < 0.01 vs. saline-treated Cav3.1 KO mice. Error bars represent the SEM. DA: dopamine, 5-HT: serotonin, AUC: area under the receiver operator characteristic curve, KO: Cav3.1 KO mice.