Table 1. Peptides sequence, identity and similarity of the six B-cell linear epitopes predicted in the proteins of L. infantum and its orthologs in Homo sapiens, T. cruzi (strains CL Brenner and DM28c), L. donovani (strain BPK282A) and L. major (strain Friedlin).
| Peptide* | Protein ID | Coordinate | Bepipred score | H. sapiens | T. cruzi CL Brenner | T. cruzi DM28c | L. donovani BPK282A1 | L. major Friedlin | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Inicial | Final | Id (%) | Si (%) | Id (%) | Si (%) | Id (%) | Si (%) | Id (%) | Si (%) | Id (%) | Si (%) | |||
| 1 | LinJ.30.2730 | 290 | 303 | 1.63 | 64.3 | 64.3 | 52.0 | 64.3 | 53.0 | 64.3 | 100.0 | 100.0 | 64.2 | 64.2 |
| 2 | LinJ.30.2730 | 361 | 388 | 1.87 | 42.8 | 53.6 | 57.0 | 64.3 | 62.0 | 62.0 | 100.0 | 100.0 | 96.0 | 96.0 |
| 3 | LinJ.32.0280 | 1198 | 1211 | 1.71 | 50.0 | 50.0 | 67.0 | 67.0 | 50.0 | 57.1 | 100.0 | 100.0 | 92.8 | 92.8 |
| 4 | LinJ.32.0280 | 1259 | 1275 | 1.84 | 58.8 | 58.8 | 58.8 | 64.7 | 58.8 | 58.8 | 100.0 | 100.0 | 64.7 | 64.7 |
| 5 | LinJ.27.0980 | 84 | 95 | 2.00 | 58.3 | 66.6 | 62.0 | 66.6 | 58.3 | 66.6 | 100.0 | 100.0 | 100.0 | 100.0 |
| 6 | LinJ.27.0980 | 196 | 215 | 2.12 | 50.0 | 50.0 | 52.9 | 52.9 | 50.0 | 60.0 | 100.0 | 100.0 | 95.0 | 95.0 |
*Epitope sequence: Peptide-1, SGAPRANNSGDASA; Peptide-2, GLSGEGSPASPEPRLAGGGGGADTQSTT; Peptide-3, DGKPKENQKTARES; Peptide-4, VADSGSASSEDGGSAKP; Peptide-5, PRKADPNDTTPQ; Peptide-6, GDSPPSDSPQNNQDRNRNQN.
Abbreviations: Id (%), Identity (%); Si (%), Similarity (%).