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. 2018 Sep 25;19(11):1065–1071. doi: 10.1080/15384047.2018.1480291

Figure 4.

Figure 4.

FOXD4 bounded to the promoter of SNAI3 and regulated SNAI3/Ecad expression. (A-B) Luciferase activity was measured after co-transfecting siFOXD4 or pcDNA3.1- FOXD4, and luciferase reporters containing the promoter region of SNAI3, into LoVo and SW480 cells. (C-E) The enrichment of FOXD4 on the promoter of SNAI3 was detected by ChIP assay of LoVo and SW480 cells transfected with siFOXD4 or pcDNA3.1- FOXD4. (F)The expression of CDH1 was measured by quantitative real-time PCR of LoVo cells co-transfected with pcDNA3.1- FOXD4 and siSNAI3. (*p < 0.05, **p < 0.01, ***p < 0.001).