Table 3.

Histology of Biopsy and RPE.

		Insulin	Metformin	Other Antidiabetics	No DM-Medication	Total
p = 0.932 (Fisher’s exact test for comparison between groups)
Biopsy GS ≤ 6	n	17	33	14	24	88
	%	63.0%	61.1%	70.0%	58.5%	62.0%
Biopsy GS 7	n	6	16	5	13	40
	%	22.2%	29.6%	25.0%	31.7%	28.2%
Biopsy GS ≥ 8	n	4	5	1	4	14
	%	14.8%	9.3%	5.0%	9.8%	9.8%
Total	n	27	54	20	41	142
	%	100.0%	100.0%	100.0%	100.0%	100.0%
p = 0.212 (Fisher’s exact test for comparison between groups)
RPE GS ≤ 6	n	13	11	8	16	48
	%	40.6%	18.0%	29.6%	34.7%	28.9%
RPE GS 7	n	15	41	14	21	91
	%	46.9%	67.2%	51.9%	45.7%	54.8%
RPE GS ≥ 8	n	4	9	5	9	27
	%	12.5%	14.8%	18.5%	19.6%	16.3%
Total	n	32	61	27	46	166
	%	100.0%	100.0%	100.0%	100.0%	100.0%
p = 0.251 (Fisher’s exact test for comparison between groups)
Same Histology	n	13	20	4	12	49
	%	48.1%	37.0%	20.0%	30.0%	34.8%
Under-grading	n	11	30	14	20	75
	%	40.7%	55.6%	70.0%	50.0%	53.1%
Over- grading	n	3	4	2	8	17
	%	11.2%	7.4%	10.0%	20.0%	12.1%
Total	n	27	54	20	40	141
	%	100.0%	100.0%	100.0%	100.0%	100.0%
p = 0.696 (Fisher’s exact test for comparison between groups)
≤ pT2c	n	21	43	18	28	110
	%	65.6%	70.5%	66.7%	59.6%	65.9%
≥ pT3a	n	11	18	9	19	57
	%	34.4%	29.5%	33.3%	40.4%	34.1%
Total	n	32	61	27	47	167
	%	100.0%	100.0%	100.0%	100.0%	100.0%
p = 0.603 (Fisher’s exact test for comparison between groups; Rx excluded)
R0	n	19	42	18	23	102
	%	59.4%	68.8%	66.7%	48.9%	61.1%
R1	n	8	17	7	16	48
	%	25.0%	27.9%	25.9%	34.1%	28.7%
Rx	n	5	2	2	8	17
	%	15.6%	3.3%	7.4%	17.0%	10.2%
Total	n	32	61	27	41	167
	%	100.0%	100.0%	100.0%	100.0%	100.0%