Table 2.
Outcomes of VA-ECMO-treated patient according to neurological complication status
| Characteristic | No damage (n = 813) | Brain injury | |
|---|---|---|---|
| Ischemic stroke (n = 42) | Intracranial bleeding (n = 20) | ||
| At ECMO onset | |||
| Gas-exchange valueb | |||
| pH | 7.32 [7.17;7.42] | 7.30 [7.21;7.42] | 7.30 [7.15;7.41] |
| PaCO2 | 32.1 [26.2;38.9] | 33.4 [27.4;37.9] | 35.9 [26.3;42.4] |
| PaO2 | 160 [97;289] | 144 [88;212] | 240 [99;311] |
| Lactates | 6 [2.7;11.1] | 6 [2.4;10] | 7.3 [4.6;11] |
| Platelet count (giga/L)a,c | 155 [96;216] | 165.5 [100;237] | 80 [59;175] |
| Fibrinogen (g/L) | 3 [2;5] | 3.2 [2.4;4.8] | 3 [1.7;4] |
| Prothrombin time (%) | 45 [30;62] | 52 [32;66] | 30 [27;54] |
| aPTT, patient/normal-value ratio | 1.6 [1.2;2.3] | 1.5 [1.2;2.1] | 1.9 [1.6;3.2] |
| ECMO duration before neurological event (days)a | – | 11 [6;18] | 5 [2;9] |
| ICU length of stay (days)a | 11 [4;22] | 18 [9;30] | 5 [2;20] |
| Hospital mortalitya | 390 (48) | 24 (57) | 18 (90) |
| 1-year mortality | NA | 31 (73) | 19 (95) |
Results are expressed as number (%) or median [27th;75th percentile]
VA-ECMO venoarterial-extracorporeal membrane oxygenation, ICU intensive care unit, aPTT activated partial thrombin time, NA not available
aP < 0.05 for between-group comparisons
bValues are missing for 112 patients: 106 with no damage, 5 with ischemic stroke and 1 with intracranial bleeding
cValues are missing for 60 patients: 52 without no damage, 6 with ischemic stroke and 2 with intracranial bleeding