Table 1.
Baseline characteristics of the patients included in this study
| SeHCAT category | |||||
|---|---|---|---|---|---|
| Variables | Total | Severe | Moderate | Mild | Borderline |
| n=114 | (0–5%)(n=34) | (5–10%)(n=19) | (10–15%)(n=29) | (>15%)(n=32) | |
| n (%) | n (%) | n (%) | n (%) | n (%) | |
| Gender | |||||
| Female | 65 (57.0) | 24 (37) | 15 (23) | 14 (22) | 12 (18) |
| Male | 49 (43.0) | 10 (20) | 4 (8) | 15 (31) | 20 (41) |
| Age, years | |||||
| Median (range) | 64 (23–86) | 61 (30–84) | 65 (23–85) | 63 (28–80) | 67 (40–86) |
| Interquartile range | 55–71 | 52–71 | 56–69 | 50–70 | 58–74 |
| Weight, kg | |||||
| Median (range) | 77 (39–127) | 71 (39–127) | 71 (48–118) | 78 (51–117) | 82 (45–118) |
| Interquartile range | 64–90 | 55–84 | 62–95 | 65–84 | 66–100 |
| BMI | |||||
| Median (range) | 27 (16–45) | 27 (17–38) | 28 (18–44) | 27 (19–39) | 29 (16–45) |
| Interquartile range | 23–31 | 20–31 | 22–35 | 24–29 | 23–31 |
| Tumour site | |||||
| Upper GI | 10 (9) | 2 (20) | 0 | 3 (30) | 5 (50) |
| Lower GI | 25 (22) | 8 (32) | 7 (28) | 5 (20) | 5 (20) |
| Urology | 30 (26) | 8 (27) | 2 (7) | 8 (27) | 12 (40) |
| Gynaecological | 31 (27) | 11 (35) | 5 (16) | 8 (26) | 7 (23) |
| Haematology | 8 (7) | 3 (38) | 1 (12) | 2 (25) | 2 (25) |
| Other** | 36 (32) | 12 (33) | 10 (28) | 5 (14) | 9 (25) |
| GI surgery | 60 (53) | 22 (37) | 11 (18) | 13 (22) | 14 (23) |
| Oesophago-gastric | 6 (10) | 0 | 0 | 2 (33) | 4 (67) |
| Pancreatic | 4 (7) | 0 | 1 (25) | 1 (25) | 2 (50) |
| Biliary | 1 (2) | 1 (100) | 0 | 0 | 0 |
| Hepatic | 5 (8) | 1 (20) | 2 (40) | 0 | 2 (40) |
| Stoma | 15 (25) | 7 (47) | 3 (20) | 4 (27) | 1 (7) |
| Small bowel | 9 (15) | 7 (78) | 1 (11) | 1 (11) | 0 |
| Right colon | 14 (23) | 6 (43) | 2 (14) | 3 (21) | 3 (21) |
| Left colon | 0 | 0 | 0 | 0 | 0 |
| Anterior resection | 12 (20) | 2 (17) | 4 (33) | 3 (25) | 3 (25) |
| Other surgery | 26 (43) | 7 (27) | 6 (23) | 7 (27) | 6 (23) |
| Coexisting treated disorders | 61 (55) | 19 (31) | 9 (15) | 18 (30) | 15 (25) |
| SIBO | 51 (84) | 17 (33) | 9 (18) | 14 (27) | 11 (22) |
| Pancreatic insufficiency | 21 (34) | 6 (29) | 3 (14) | 7 (33) | 5 (24) |
| Prescribed medication | 86 (75) | 32 (37) | 17 (20) | 18 (21) | 19 (22) |
| Loperamide | 37 (43) | 9 (24) | 6 (16) | 8 (22) | 14 (38) |
| Normacol | 22 (26) | 1 (5) | 7 (32) | 9 (41) | 5 (23) |
| Colesevelam | 55 (64) | 30 (55) | 15 (27) | 6 (11) | 4 (7) |
| Senna | 7 (8) | 0 | 2 (29) | 1 (14) | 4 (57) |
| Sodium docusateLactulose | 01 (1) | 0 | 0 | 0 | 1 (100) |
| Laxido | 1 (1) | 0 | 1 (100) | 0 | 0 |
| Daily colesevelam | 53 (46) | 28 (53) | 15 (28) | 6 (11) | 4 (8) |
| Daily cholestyramine | 0 | ||||
**Breast (n=5), endometrium (n=1), hepatic (n=1), leukaemia (n=3), metastatic disease (n=16), neuroendocrine (n=1), prostate (n=2), rectal (n=1), sarcoma (n=1), vaginal vault (n=1) and unknown (n=4).
BMI = body mass index; GI = gastrointestinal; SeHCAT = selenium-75 homocholic acid taurine; SIBO = small intestinal bacterial overgrowth