Table 2.
Patient GSRS symptom occurrence change from pre- to post-treatment assessment
| Symptom Frequency of occurrence | n | Initial assessment, n (%) | Follow-up, n (%) | McNemar p-value | ||
|---|---|---|---|---|---|---|
| Never/occasional | Frequent/CMCL | Never/occasional | Frequent/CMCL | |||
| Urgency to open bowels | 107 | 55 (51) | 52 (49) | 72 (67) | 35 (33) | 0.005 |
| Abdominal bloating | 99 | 69 (70) | 30 (30) | 77 (78) | 22 (22) | 0.100 |
| Faecal incontinence | 96 | 70 (73) | 26 (27) | 81 (84) | 15 (16) | 0.013 |
| Flatulence | 106 | 60 (57) | 46 (43) | 76 (72) | 30 (28) | 0.005 |
| Abdominal pain | 107 | 60 (56) | 47 (44) | 77 (72) | 30 (28) | 0.001 |
| Steatorrhoea | 91 | 73 (80) | 18 (20) | 83 (91) | 8 (9) | 0.031 |
| Nocturnal defecation | 104 | 74 (71) | 30 (29) | 87 (84) | 17 (16) | 0.001 |
| Tenesmus | 104 | 65 (63) | 39 (37) | 70 (67) | 34 (33) | 0.359 |
| Belching | 107 | 84 (79) | 23 (21) | 96 (90) | 11 (10) | 0.008 |
| Nausea | 106 | 84 (79) | 22 (21) | 94 (89) | 12 (11) | 0.021 |
| Vomiting | 107 | 97 (91) | 10 (9) | 103 (96) | 4 (4) | 0.031 |
| Heartburn | 107 | 89 (83) | 18 (17) | 96 (90) | 11 (10) | 0.144 |
| Borborygmi | 106 | 65 (61) | 41 (39) | 81 (76) | 25 (24) | 0.004 |
CMCL = causes major changes in life; GSRS = gastrointestinal symptom rating scale