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. 2018 Dec 20;8:18004. doi: 10.1038/s41598-018-36404-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Association of postCI outcomes with DoD and age at CI operation. (A) When DoD was longer than 10 years, postoperative WRS was significantly lower compared to when DoD was shorter than 10 years. The difference in postCI WRS became even larger when comparing patients with DoD of 20 years or longer to those with DoD of shorter than 10 years. (B) PostCI WRS significantly correlated with age at CI operation in subgroups of patients with DoD of 0–4.9 years and 5–9.9 years. (C) No such correlation was found in patients with DoD of 10–19 years, and those with 20 years or longer as much larger variability across individuals were observed in these groups. In (B), and (C), transparent data points and lines were used to help the comparison between the four subgroups.