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. 2018 Dec 20;8:18000. doi: 10.1038/s41598-018-36125-5

Figure 8.

Figure 8

There is no direct agonist for ASIC4 and BASIC among the 109 neuropeptides. (a,b) Top, representative current traces of ASIC4 (a) or BASIC (b) expressing oocytes activated with divalent free solution (div free; red bars). Controls (ctrl; black bars) before each peptide mix (M; blue bars) contained the solvent in its respective concentration. Peptides were applied at pH 7.4. Bottom, bar graphs showing the mean current amplitudes; error bars show the SD. *p < 0.05 (paired Student’s t-test followed by Bonferroni correction).