Figure 3.

Contour plots for predicted mean spread area (a) and mean cell AR (b) in the ${\rho }_{\text{col}}-E_{\text{sub}}$ space. (c) The predicted cell area (mean$\pm$SD) and (d) cell AR (mean$\pm$SD) as a function of surface collagen density ${\rho }_{\text{col}}$ for cells spread on substrates of different stiffness (red: rigid; yellow: 32 kPa; green: 8 kPa). Sample cell spread states are shown for a given substrate in (a and b). To see this figure in color, go online.