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. 2018 Dec 14;11:459. doi: 10.3389/fnmol.2018.00459

Table 2.

Thermodynamic parameters of binding of D2R peptide to NCS-1 in 20 mM Tris-HCl buffer (pH 8.0), 150 mM NaCl, 5 mM CaCl2 in the presence or in the absence of 100 μM ZnCl2.

Ca2+ Ca2++Zn2+
N 0.676 ± 0.091 0.508 ± 0.102
KA, M-1 (3.320 ± 0.568) × 104 (11.800 ± 2.550) × 104
KD, M 30.12 × 10-6 8.47 × 10-6
ΔH, kcal M-1 -3.0 ± 0.5 -3.2 ± 0.8
ΔS, cal K-1 M-1 10.6 12.4
ΔG, kcal M-1 -6.2 -6.9