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. 2018 Dec 14;9:736. doi: 10.3389/fendo.2018.00736

Table 2.

Diagnostic accuracy of preoperative ultrasound for pathologic T4 papillary thyroid carcinoma.

References Country Study T4 Patients Criteria US accuracy
King et al. (34) Hong Kong SP 3/14 of PTC A 0/3
Choi et al. (35) South Korea SR 1/299 of PTC B 0/1
Park et al. (36) South Korea SP 1/94 of PTC B,C 0/1
Choi et al. (37) South Korea SR 1/722 of PTC B 1/1
Lee et al. (30) South Korea SR 3/568 of PTC B 0/3

Criteria category: A: poorly defined margin with heterogeneous echogenicity in adjacent fat or muscle or tumor invasion into the lumen; B: focal bulging out or disruption of the thyroid capsule by tumor or more than 25% of perimeter of the tumor was abutting the thyroid capsule; C, tumor diameter. SP, single center prospective; SR, single center retrospective; PTC, papillary thyroid carcinoma; US, ultrasound.