Table 5.
Cervical lymph node recurrence rate in different papillary thyroid microcarcinoma cohorts with immediate surgery.
| References | Country | No. of patients | Gross ETE (n, %) | Clinical LN (n, %) | RAI (n, %) | FU (years) | TR (n, %) | LNR (n, %) |
|---|---|---|---|---|---|---|---|---|
| Wada et al. (53) | Japan | 259 | N/A | 24 (9.3) | N/A | 5.1 | 6 (2.3) | 5(1.9) |
| Pelizzo et al. (54) | Italy | 403 | N/A | N/A | 260 (60.5) | 8.5 | 6(1.5) | 1(0.2) |
| Hay et al. (55) | USA | 900 | N/A | 131 (14.6) | 155 (17) | 17.2 | 51(5.7) | 36 (4) |
| Besic et al. (56) | Slovenia | 254 | N/A | 51 (20.1) | 124 (49) | 4.7 | 7 (2.7) | 6(2.4) |
| Mercante et al. (57) | Italy | 445 | N/A | 37 (8.3) | 389 (87.4) | 5.3 | 17(3.8) | 13(2.9) |
| So et al. (58) | South Korea | 551 | 4 (0.7) | 0 | 444 (80.6) | 3.4 | 1(0.2) | 0 |
| Moon et al. (59) | South Korea | 288 | 0 | 10 (3.5) | 114 (39.6) | 6 | 12 (4.2) | 7(2.4) |
| Londero et al. (60) | Denmark | 406 | N/A | N/A | 161(40) | 8 | 15(3.7) | 7(1.7) |
| Lee et al. (61) | South Korea | 2014 | 18 (0.9) | N/A | 51(2.5) | 11.2 | 126(6.3) | 98(4.9) |
| Gschwandtner et al. (62) | Austria | 1391 | N/A | N/A | 255 (18.3) | 7 | 5(0.4) | 5(0.4) |
| Kim et al. (63) | South Korea | 5656 | 210 (3.7) | N/A | N/A | 5.1 | 126(2.2) | 122(2.2) |
| Cecoli et al. (64) | Italy | 437 | 0 | 0 | 152 (38.7) | 5.8 | 6(1.4) | 3(0.7) |
| Kim et al. (65) | South Korea | 8676 | 0 | 0 | 3,863 (44.5) | 5.4 | 139(1.6) | 105 (1.2) |
ETE, extrathyroidal extension; LN, lymph node; RAI, radioactive iodine; FU, follow up; TR, total recurrence; LNR, lymph node recurrence; N/A, not available.