Fig. 3.
MPB GWAS. a Workflow diagram. b, c Manhattan plots for the autosomal GWAS (b) and the XWAS (c), depicting p-values from the BOLT-LMM24 infinitesimal mixed-model association test. Green points denote 26 GWS SNPs identified by the COJO25 analysis. Chromosome 23 is the X-chromosome and chromosome PAR1 is pseudo-autosomal region 1. d LD plot for the p22.31-q13.2 region, containing jointly significant X-chromosome SNPs from the COJO25 analysis. e QQ-plot for the aggregated set of autosomal and X-chromosome GWAS P-values