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. 2018 Dec 14;9:664. doi: 10.3389/fpsyt.2018.00664

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Copyright © 2018 Durant, Paterson, Turton, Wilson, Myers, Muthukumaraswamy, Venkataraman, Mick, Paterson, Jones, Nahar, Cordero, Nutt and Lingford-Hughes.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differences in change-from-baseline theta power between placebo and 60 mg baclofen, shown with both eyes open (EO) and eyes shut (ES) at 5 time points in controls (n = 7). Contrasts were performed between placebo and baclofen (t statistics of difference between the difference at baseline) to create one image per time point. This represents a subtraction of column 1 (placebo) from column 3 (60 mg baclofen) as depicted in Figure 7. Red indicates relatively more power following baclofen relative to placebo. Electrodes with significant differences between placebo and baclofen are shown with a white cross, corresponding to p < 0.05, FDR corrected.