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Response of (myo)fibroblasts subjected to 250 nM verteporfin (VP) for 24 and 48 hours. mRNA levels of Yes Activated Protein did not change, whereas mRNA levels of extracellular matrix molecules (COL1A1, COL5A1, EDA-FN), collagen-modifying enzymes (SERPINH1, PLOD2, LOXL2), and the pro-fibrotic markers CCN2 and ACTA2 were attenuated by VP. * = P < .05.
