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. 2018 Nov 10;115(12):2336–2347. doi: 10.1016/j.bpj.2018.10.031

Table 1.

Measured CMC and CVC Ranges for NA, DA, and DDA Solutions at pH 7.8

Fatty Acid CMC
CVC
Literature
Fluorescence (mM) DLSa
NMR Turbidity Fluorescence CMCb (mM) CVCb (mM)
NA 50–70 50–70 mM NDc NDc 150–200 mM 110 85
DA 20–22 22–30 mM 49–52 mM 55–60 mM 55–60 mM 28.8 43
DDA 3.6–4.5 NMd 4.7–5.6 mM 5 mM 5–6 mM 1.58 22.5
SDS 7–8 8–8.5 mM no transition to vesicles 8.2
Triton-X 0.25–0.30 no transition to vesicles 0.25
a

CMC was determined by the concentration at which signal began to fluctuate widely.

b

Published CMC and CVC values were determined under different conditions and at different pH (29, 42) and are tabulated to emphasize the importance of doing the measurements under the conditions used in this study.

c

No transition was detected with this technique.

d

DDA solutions were not measured by DLS due to issues with solidification during samples preparation.