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Analysis of the penetration of IL-24 in PC-3 tumor tissues. A total of 10 μg/g of IL-24 or IL-24-iRGD was injected into the tail vein of PC-3–bearing mice. After 3 and 7 hours of treatment, the penetration of IL-24 in PC-3 xenograft tumors was detected by immunofluorescence staining. n = 4; magnification, ×400. Red staining indicates IL-24 protein, and blue represents DAPI staining, indicating the nucleus. DAPI, 4′,6-diamidino-2-phenylindole.
