Table 1.
Study | Year | Patient (n) |
DAPT (months) | Follow-Up (months) | Anti-Proliferative Drug |
Outcomes | ||
---|---|---|---|---|---|---|---|---|
PF-DES | DP-DES | PF-DES | DP-DES | |||||
BioFreedom FIM [19] | 2016 | 122 | 60 | 6 | 60 | Biolimus | Paclitaxel | Definite or probable ST, MI, cardiac death, all-cause death, TLR, TVR |
Dang [20] | 2012 | 50 | 55 | 6 | 12 | Paclitaxel | Sirolimus | Definite or probable ST, MI, cardiac death, all-cause death, TLR |
ISAR-TEST [21] | 2013 | 225 | 225 | 6 | 60 | Sirolimus | Paclitaxel | Definite or probable ST, MI, cardiac death, all-cause death, TLR |
ISAR-TEST-2 [16] | 2010 | 333 | 335 | 12 | 24 | Sirolimus/Probucol | Sirolimus | Definite or probable ST, MI, all-cause death |
ISAR-TEST-3 [17] | 2009 | 201 | 202 | 12 | 24 | Sirolimus | Sirolimus | Definite or probable ST, MI, all-cause death, TLR |
ISAR-TEST-5 [22] | 2016 | 2002 | 1000 | 6 | 60 | Sirolimus/Probucol | Zotarolimus | Definite or probable ST, MI, cardiac death, all-cause death, TLR, TVR |
LIPSIA Yukon [26] | 2014 | 118 | 114 | 12 | 60 | Sirolimus | Paclitaxel | Definite or probable ST, MI, cardiac death, all-cause death, TLR, TVR |
Nano [27] | 2014 | 132 | 136 | 12 | 24 | Sirolimus | Sirolimus | Definite or probable ST, MI, cardiac death, all-cause death, TVR |
NEXT [18] | 2012 | 148 | 148 | 6 | 12 | Amphilimus | Paclitaxel | Definite or probable ST, MI, cardiac death, all-cause death, TLR, TVR |
ReCre8 [24] | 2018 | 747 | 744 | 12 | 12 | Amphilimus | Zotarolimus | Definite or probable ST, MI, cardiac death, all-cause death, TLR |
RESERVOIR [23] | 2016 | 56 | 56 | 12 | 12 | Amphilimus | Everolimus | MI, cardiac death |
Shiratori [25] | 2014 | 84 | 80 | 6 | 24 | Paclitaxel | Paclitaxel | Definite or probable ST, MI, cardiac death, all-cause death, TLR, TVR |
Zhang [28] | 2013 | 327 | 321 | 12 | 24 | Paclitaxel | Sirolimus | Definite or probable ST, MI, cardiac death, all-cause death, TVR |
DAPT = dual antiplatelet therapy; DP-DES = durable polymer drug-eluting stents; MI = myocardial infarction; PF-DES = polymer-free drug-eluting stents; ST = stent thrombosis; TLR = target lesion revascularization; TVR = target vessel revascularization.